The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2018
Filed:
Feb. 20, 2009
Applicants:
Simon Mark Jackson, San Carlos, CA (US);
Derek Evan Piper, Santa Clara, CA (US);
Inventors:
Simon Mark Jackson, San Carlos, CA (US);
Derek Evan Piper, Santa Clara, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61K 39/395 (2006.01); A61K 38/48 (2006.01); C12N 9/64 (2006.01); A61K 45/06 (2006.01); A61K 31/22 (2006.01); A61K 31/366 (2006.01); A61K 31/40 (2006.01); A61K 31/405 (2006.01); A61K 31/44 (2006.01); A61K 31/47 (2006.01); A61K 31/505 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12Y 304/21061 (2013.01); A61K 31/22 (2013.01); A61K 31/366 (2013.01); A61K 31/40 (2013.01); A61K 31/405 (2013.01); A61K 31/44 (2013.01); A61K 31/47 (2013.01); A61K 31/505 (2013.01); A61K 38/482 (2013.01); A61K 45/06 (2013.01); C12N 9/6454 (2013.01); A61K 38/00 (2013.01);
Abstract
Neutralizing PCSK9 variants that interact with low density lipoprotein receptor (LDLR) are described. Methods and compositions for treating disorders by administering a pharmaceutically effective amount of a neutralizing PCSK9 variant are described.