The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2018
Filed:
Jun. 04, 2014
Applicants:
The Johns Hopkins University, Baltimore, MD (US);
Virginia Commonwealth University, Richmond, VA (US);
Inventors:
Paul B. Fisher, Richmond, VA (US);
Swadesh K. Das, Richmond, VA (US);
Mitchell E. Menezes, Richmond, VA (US);
Devanand Sarkar, Richmond, VA (US);
Martin G. Pomper, Baltimore, MD (US);
Assignees:
The Johns Hopkins University, Baltimore, MD (US);
Virginia Commonwealth University, Richmond, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/85 (2006.01); C12N 15/64 (2006.01); C07K 14/47 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 38/20 (2006.01); A61K 41/00 (2006.01); A61K 49/00 (2006.01); A61N 7/00 (2006.01); C07K 14/36 (2006.01); C07K 14/465 (2006.01); C07K 14/54 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01); C12N 15/62 (2006.01); B82Y 5/00 (2011.01); B82Y 15/00 (2011.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); A61K 38/164 (2013.01); A61K 38/1703 (2013.01); A61K 38/20 (2013.01); A61K 41/0028 (2013.01); A61K 48/0058 (2013.01); A61K 48/0075 (2013.01); A61K 49/00 (2013.01); A61N 7/00 (2013.01); C07K 14/36 (2013.01); C07K 14/465 (2013.01); C07K 14/47 (2013.01); C07K 14/54 (2013.01); C12N 7/00 (2013.01); C12N 15/625 (2013.01); C12N 15/64 (2013.01); C12N 15/86 (2013.01); G01N 33/50 (2013.01); G01N 33/574 (2013.01); A61K 48/00 (2013.01); A61N 2007/0039 (2013.01); B82Y 5/00 (2013.01); B82Y 15/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/035 (2013.01); C12N 2710/10043 (2013.01); C12N 2799/02 (2013.01); C12N 2799/022 (2013.01); C12N 2800/22 (2013.01); C12N 2810/855 (2013.01); C12N 2830/002 (2013.01); C12N 2830/008 (2013.01);
Abstract
The presently disclosed subject matter relates to compositions and methods directed to cancer theranostic nucleic acid constructs that permit simultaneous cancer-specific viral replication, expression of a diagnostic gene product, and expression of a therapeutic gene.