The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2018

Filed:

Aug. 27, 2014
Applicant:

Deutsches Krebsforschungszentrum, Heidelberg, DE;

Inventors:

Philipp Beckhove, Heidelberg, DE;

Michael Boutros, Heidelberg, DE;

Nisit Khandelwal, Heidelberg, DE;

Marco Breinig, Bad Rappenau, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C12N 15/113 (2010.01); G01N 33/50 (2006.01); A61K 31/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61K 31/00 (2013.01); G01N 33/5011 (2013.01); G01N 33/5023 (2013.01); G01N 33/6893 (2013.01); C12N 2310/14 (2013.01); G01N 2333/705 (2013.01);
Abstract

The present invention relates to a compound selectively binding to a sensory receptor or selectively altering the expression of a sensory receptor for use in a method for treating or preventing a disease associated with a pathologic cellular cytotoxic T cell (CTL) response. Further, the invention relates to means for detecting a sensory receptor for use in a method for diagnosing cellular resistance against CTL response in a patient. The invention further embraces a method for determining the resistance of a cell against a CTL response in vitro and to a method for identifying agents that influence the response of cells to CTLs.


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