The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2018
Filed:
Aug. 26, 2011
Applicants:
Gordon Keller, Toronto, CA;
April M. Craft, Toronto, CA;
Nicole C. Dubois, Toronto, CA;
Inventors:
Assignee:
UNIVERSITY HEALTH NETWORK, , CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01); G01N 33/53 (2006.01); C12N 5/077 (2010.01); C12Q 1/68 (2018.01); G01N 33/569 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12Q 1/6881 (2013.01); C12N 2501/115 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/165 (2013.01); C12N 2501/415 (2013.01); C12N 2506/00 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01); C12Q 2600/158 (2013.01); G01N 33/5073 (2013.01); G01N 33/53 (2013.01); G01N 33/56966 (2013.01);
Abstract
The present invention relates to in vitro methods of enriching populations of human pluripotent stem cells that are induced to differentiate to cardiomyocyte progenitor cells and cardiomyocyte cells. The cell populations can be enriched by isolating cells that express SIRPA. The invention also related to in vitro-enriched populations of cardiomyocyte cells and cardiomyocyte progenitor cells obtained from populations of pluripotent stem.