The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2018
Filed:
Jul. 30, 2013
Applicant:
Hong-jin Kim, Seoul, KR;
Inventors:
Hong-Jin Kim, Seoul, KR;
Hyoung Jin Kim, Seoul, KR;
Assignee:
Other;
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); C07K 14/025 (2006.01); C12N 7/00 (2006.01); C12N 7/02 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 39/00 (2013.01); C12N 2710/20034 (2013.01); C12N 2710/20051 (2013.01);
Abstract
Provided is a method of purifying human papillomavirus (HPV) L1 proteins with high purity and high efficiency. According to the purification method, a purification purity and yield of HPV L1 proteins can be considerably increased when heating/chilling is formed by treating a cell homogenate with a reducing agent. In addition, VLPs of the HPV L1 protein purified by the purification method have excellent antigenicity and immunogenicity.