The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2018
Filed:
Aug. 28, 2014
Applicant:
Mars, Incorporated, McLean, VA (US);
Inventors:
Michael Van Zandt, McLean, VA (US);
Adam Golebiowski, McLean, VA (US);
Min Koo Ji, McLean, VA (US);
Darren Whitehouse, McLean, VA (US);
Todd Ryder, McLean, VA (US);
Raymond Paul Beckett, McLean, VA (US);
Assignee:
Mars, Incorporated, McLean, VA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01);
Abstract
Compounds according to Formula I and Formula II are potent inhibitors of Arginase I and II activity: where R, R, R, R, R, R, R, R, R, D, M, X, and Y are defined as set forth in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use for treating or preventing a disease or a condition associated with arginase activity.