The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2018

Filed:

Dec. 14, 2015
Applicant:

Shenyang Sunshine Pharmaceutical Co. Ltd., Shenyang, Liaoning, CN;

Inventors:

Yunlong Zhou, Nanjing, CN;

Suixiong Cai, San Diego, CA (US);

Guangfeng Wang, Shanghai, CN;

Lingling Jiao, Taizhou, CN;

Ping Min, Shanghai, CN;

Yu Jing, Taizhou, CN;

Ming Guo, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 1/00 (2018.01); A61P 7/06 (2018.01); A61P 19/02 (2018.01);
Abstract

Disclosed are a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, a preparation method thereof, pharmaceutical compositions and uses thereof in the preparation of a medicine for inhibiting HIF prolyl hydroxylase or a medicine for promoting the generation of endogenous EPO, wherein in the formula (I), Rand Rare each independently hydrogen; Ris hydrogen or Calkyl; and Ar is an aromatic ring or an heteroaromatic ring selected from a naphthalene ring, a pyridine ring, a thiophene ring, a furan ring and a substituted benzene ring.


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