The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2018
Filed:
Sep. 19, 2014
Karyopharm Therapeutics Inc., Newton, MA (US);
Erkan Baloglu, Stoneham, MA (US);
Sharon Shacham, Newton, MA (US);
William Senapedis, Millis, MA (US);
Dilara McCauley, Arlington, MA (US);
Yosef Landesman, Brookline, MA (US);
Gali Golan, Mesilat Zion, IL;
Ori Kalid, Pardes Hanna, IL;
Sharon Shechter, Andover, MA (US);
Karyopharm Therapeutics Inc., Newton, MA (US);
Abstract
The invention generally relates to compounds represented by Structural Formula I: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders (e.g., PAK-mediated, for example, PAK4-mediated, diseases and disorders).