The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2018

Filed:

Aug. 29, 2014
Applicant:

Council of Scientific & Industrial Research, New Delhi, IN;

Inventors:

Sabyasachi Sanyal, Lucknow, IN;

Atul Kumar, Lucknow, IN;

Naibedya Chattopadhyay, Lucknow, IN;

Jawahar Lal, Lucknow, IN;

Arun Kumar Trivedi, Lucknow, IN;

Dipak Datta, Lucknow, IN;

Srikanta Kumar Rath, Lucknow, IN;

Tahseen Akhtar, Lucknow, IN;

Shailendra Kumar Dhar Dwivedi, Lucknow, IN;

Manisha Yadav, Lucknow, IN;

Bandana Chakravarti, Lucknow, IN;

Abhishek Kumar Singh, Lucknow, IN;

Jay Sharan Mishra, Lucknow, IN;

Nidhi Singh, Lucknow, IN;

Anil Kumar Tripathi, Lucknow, IN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 251/48 (2006.01); C07C 251/58 (2006.01); C07C 251/60 (2006.01); C07C 55/07 (2006.01); C07C 57/15 (2006.01); C07C 59/255 (2006.01); C07C 59/265 (2006.01); C07C 249/08 (2006.01); C07C 319/02 (2006.01); C07C 321/26 (2006.01); C07D 295/088 (2006.01);
U.S. Cl.
CPC ...
C07C 251/48 (2013.01); C07C 55/07 (2013.01); C07C 57/15 (2013.01); C07C 59/255 (2013.01); C07C 59/265 (2013.01); C07C 249/08 (2013.01); C07C 251/58 (2013.01); C07C 251/60 (2013.01); C07C 319/02 (2013.01); C07C 321/26 (2013.01); C07D 295/088 (2013.01);
Abstract

The present invention relates to substituted aryl naphthyl methanone oximes of general formula (I), their process for preparation and their derivatives, salts, pharmaceutical composition thereof and their use in treatment of chronic myelogenous leukemia, acute myelogenous leukemia, lymphoma, multiple myeloma, solid tumor forming cell-lines including such as breast cancer, endometrial cancer colon cancer, prostate cancer and killing of drug resistant cancer stem cells, as subject in need thereof.


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