The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2018

Filed:

May. 22, 2015
Applicant:

Boehringer Ingelheim Vetmedica Gmbh, Ingelheim am Rhein, DE;

Inventors:

Gregor Meyers, Neuenkirchen-Wampen, DE;

Sabine Wirtz, Aachen, DE;

Assignee:

Boehringer Ingelheim Vetmedica GmbH, Ingelheim am Rhein, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); G01N 33/569 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C12N 7/00 (2013.01); G01N 33/56983 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/552 (2013.01); C12N 2770/24321 (2013.01); C12N 2770/24322 (2013.01); C12N 2770/24334 (2013.01); C12N 2770/24362 (2013.01); G01N 2333/185 (2013.01);
Abstract

The present invention relates i.a. to a CSFV (classical swine fever virus) comprising a substitution of proline to lysine at amino acid position 44 of the E2 protein and a substitution of threonine to aspartic acid at amino acid position 45 of the E2 protein. Further, the present invention provides an immunogenic composition comprising the CSFV of the present invention and the use of the immunogenic composition for reducing the incidence of or severity in an animal of one or more clinical signs associated with CSF. Moreover, the present invention provides a method of differentiating animals infected with CSFV from animals vaccinated with the immunogenic composition of the present invention.


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