The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2018

Filed:

Jan. 09, 2012
Applicants:

Richard A. Bond, San Francisco, CA (US);

Mitchell Glass, Wilmington, DE (US);

Inventors:

Richard A. Bond, San Francisco, CA (US);

Mitchell Glass, Wilmington, DE (US);

Assignee:

INVION, INC., Seventeen Mile Rocks, AU;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/138 (2006.01); A61K 45/06 (2006.01); A61K 31/403 (2006.01); A61K 31/5377 (2006.01); A61K 9/68 (2006.01); A61K 9/70 (2006.01);
U.S. Cl.
CPC ...
A61K 31/138 (2013.01); A61K 31/403 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61K 9/0058 (2013.01); A61K 9/7023 (2013.01);
Abstract

The chronic use of p-adrenergic inverse agonists such as nadolol, carvedilol, and ICI-118,551 provides an improved method for the treatment of mucus hypersecretion in subjects with such mucus hypersecretion. One aspect of a method according to the present invention is a method of preventing or controlling mucus hypersecretion in the respiratory tract comprising administering a therapeutically effective quantity of a p-adrenergic inverse agonist to a subject with mucus hypersecretion or at risk of mucus hypersecretion. The invention further encompasses pharmaceutical compositions comprising the p-adrenergic inverse agonist and the additional compound.


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