The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2018

Filed:

Mar. 13, 2014
Applicant:

University of Rochester, Rochester, NY (US);

Inventors:

John Elfar, Rochester, NY (US);

Kuang-Ching Tseng, Rochester, NY (US);

Mark Noble, Brighton, NY (US);

Assignee:

University of Rochester, Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 31/4409 (2006.01); A61K 9/00 (2006.01); A61K 47/34 (2017.01); A61K 9/70 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1647 (2013.01); A61K 9/0024 (2013.01); A61K 9/7007 (2013.01); A61K 31/4409 (2013.01); A61K 45/06 (2013.01); A61K 47/34 (2013.01);
Abstract

Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.


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