The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2018
Filed:
Jun. 17, 2016
Applicant:
Antisense Therapeutics Limited, Toorak, Victoria, AU;
Inventor:
George Tachas, Melbourne, AU;
Assignee:
Antisense Therapeutics Limited, Toorak,Victoria, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2018.01); G01N 33/74 (2006.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61K 47/554 (2017.08); C12Q 1/6883 (2013.01); G01N 33/74 (2013.01); C12N 2310/11 (2013.01); C12N 2320/30 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/71 (2013.01); Y10T 436/143333 (2015.01);
Abstract
Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides, targeted to nucleic acid encoding growth hormone receptor. Methods of using these compounds for modulation of growth hormone receptor expression and for diagnosis and treatment of disease associated with expression of growth hormone receptor and/or insulin-like growth factor-I are provided. Diagnostic methods and kits are also provided.