The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2018
Filed:
Jan. 18, 2016
Applicants:
Daiichi Sankyo Europe Gmbh, Munich, DE;
Amgen, Inc., Thousand Oaks, CA (US);
Inventors:
Thore Hettmann, Munich, DE;
Daniel J. Freeman, Newbury Park, CA (US);
Robert Radinsky, Thousand Oaks, CA (US);
Mike Rothe, Krailling, DE;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 51/10 (2006.01); C07K 16/40 (2006.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); A61N 5/10 (2006.01); A61K 47/68 (2017.01); A61K 31/506 (2006.01); A61K 31/4709 (2006.01); A61K 31/5377 (2006.01); A61K 31/496 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/395 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61K 47/6871 (2017.08); A61N 5/10 (2013.01); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
Described herein are materials and methods for treating subjects having a HER-3 associated disease, by administering a first agent that binds to HER-3, in combination with a second agent that binds and/or inhibits another member of the HER family. The first and the second agent may be a biologic, such as an antigen-binding protein, or a small molecular tyrosine kinase inhibitor, for example.