The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2018
Filed:
Mar. 21, 2013
Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, AU;
Mireille Hanna Lahoud, East Melbourne, AU;
Anna Irene Proietto, Bulleen, AU;
Irina Caminschi, Ascot Vale, AU;
Ken Shortman, Princess Hill, AU;
Andrew Mark Lew, Essendon, AU;
Li Wu, Ascot Vale, AU;
Mark Dexter Wright, Northcote, AU;
Abstract
The present invention relates to the identification of proteins located on the cell surface of dendritic cells or precursors thereof, particularly antigen presenting dendritic cells. In particular, the present invention relates to compounds such as antibodies that bind these proteins. These compounds can be used to detect and/or enrich a subset of dendritic cells or precursors thereof. These compounds can also be used to target antigens to dendritic cells or precursors thereof to modulate a humoral and/or T cell mediated immune response to an antigen, or used to target cytotoxic agents to dendritic cells or precursors thereof involved in diseased states.