The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2018
Filed:
Feb. 05, 2014
Applicant:
Agency for Science, Technology and Research, Connexis, SG;
Inventor:
Peter Stanley Gagnon, Centros, SG;
Assignee:
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, Singapore, SG;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/14 (2006.01); C07K 16/00 (2006.01); B01D 15/36 (2006.01); C07K 1/16 (2006.01); B01D 15/34 (2006.01); C07K 1/20 (2006.01); C07K 16/30 (2006.01); B01D 15/32 (2006.01); B01D 15/38 (2006.01);
U.S. Cl.
CPC ...
C07K 1/14 (2013.01); B01D 15/34 (2013.01); B01D 15/363 (2013.01); C07K 1/165 (2013.01); C07K 1/20 (2013.01); C07K 16/00 (2013.01); C07K 16/3015 (2013.01); B01D 15/327 (2013.01); B01D 15/3828 (2013.01);
Abstract
A method of reducing the aggregate content in a protein preparation having a target protein includes contacting the protein preparation with a thio-heterocyclic cation to form a mixture, contacting the mixture with at least one functionalized solid to remove excess thio-heterocyclic cations; and optionally contacting the mixture, simultaneously or sequentially, with at least one further functionalized solid to further reduce aggregate content of the protein preparation.