The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2018

Filed:

Mar. 03, 2017
Applicants:

Tufts University, Boston, MA (US);

Boston Medical Center Corporation, Boston, MA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Paola Massari, Cambridge, MA (US);

Guillermo Madico, Natick, MA (US);

Luis de la Maza, Irvine, CA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/118 (2006.01); C07K 14/22 (2006.01); C07K 14/295 (2006.01);
U.S. Cl.
CPC ...
A61K 39/118 (2013.01); C07K 14/22 (2013.01); C07K 14/295 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/575 (2013.01); A61K 2039/6068 (2013.01);
Abstract

Purifiedmajor outer membrane protein (MOMP) has been observed to induce protection against genital and respiratory challenge in mice. MOMP contains variable domains that are highly immunogenic and elicit cross-serovar neutralizing monoclonal and polyclonal antibodies and T cell responses in animal and human models. Examples herein provide a method for vaccinating a subject againstusing a composition that is a recombinantporin that contains at least one antigenic variable domain of. The variable domains are inserted into the amino acid sequence of theporin at a position encoding a surface-exposed loop of theporin. The vaccine further contains an adjuvant that induces a Th1 response greater than a Th2 response.


Find Patent Forward Citations

Massari, Paola. (2018). Methods and compositions for vaccinating a subject for a sexually transmitted pathogen (U.S. Patent No. 9987346). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9987346

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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