The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2018
Filed:
Dec. 16, 2014
Tiumbio Co., Ltd., Gyeonggi-do, KR;
Hong-Kee Kim, Gyeonggi-do, KR;
Ho Chul Shin, Gyeonggi-do, KR;
Yoon-Jung Lee, Gyeonggi-do, KR;
Ho Soon Lee, Gyeonggi-do, KR;
Ji-Hye Lee, Seoul, KR;
Seok-chan Kang, Gyeonggi-do, KR;
Hun-Taek Kim, Seoul, KR;
TIUMBIO CO., LTD., Gyeonggi-Do, KR;
Abstract
The present invention provides a pharmaceutical composition with improved stability, comprising a fusion protein comprising Factor VII (FVII) and transferrin, as an active ingredient, wherein the transferrin is linked to the C-terminus of the FVII; and trehalose or glycine as a bulking agent. The composition can store FVII and a variant thereof stably at room temperature for a long period of time. Thus it can be used as a useful therapeutic agent for patients suffering from hemophilia or congenital FVII deficiency.