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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9987299 B1

PDFFull Text
Date of Patent:
Jun. 05, 2018

Filed:

May. 04, 2015

Methods of improving rnai in well-differentiated airway epithelia

Applicant:

University of Iowa Research Foundation, Iowa City, IA (US);

Inventors:

Paul B. McCray, Jr., Iowa City, IA (US);

Beverly L. Davidson, Iowa City, IA (US);

Michael A. Apicella, Iowa City, IA (US);

Sateesh Krishnamurthy, Iowa City, IA (US);

Assignee:

University of Iowa Research Foundation, Iowa City, IA (US);

Attorney:

Viksnins Harris Padys Malen LLP

Primary Examiner:

Kimberly Chong

Int. Cl.
CPC ...
A61K 31/713 (2006.01); A61K 31/685 (2006.01); A61K 31/715 (2006.01); A61K 45/06 (2006.01); A61K 31/7024 (2006.01); A61K 31/7032 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 31/685 (2013.01); A61K 31/7024 (2013.01); A61K 31/7032 (2013.01); A61K 31/715 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a facilitating agent followed by contacting the cell with a therapeutic RNAi agent, wherein the facilitating agent comprises a Platelet-activating factor receptor (PAFR) ligand.

Find Patent Forward Citations

McCray, Jr., Paul. (2018). Methods of improving rnai in well-differentiated airway epithelia (U.S. Patent No. 9987299). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9987299

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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