The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2018

Filed:

Jun. 26, 2015
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);

Inventors:

Meredith M. Lee, El Cerrito, CA (US);

Jelena Levi, San Francisco, CA (US);

James L. Zehnder, Menlo Park, CA (US);

James S. Harris, Jr., Stanford, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/145 (2006.01); G01N 21/64 (2006.01); A61B 5/1455 (2006.01); C12Q 1/56 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/14556 (2013.01); A61B 5/14546 (2013.01); C12Q 1/56 (2013.01); G01N 21/6428 (2013.01); A61B 5/14557 (2013.01); G01N 2021/6432 (2013.01);
Abstract

Improved monitoring of one or more blood coagulation factors is provided. Factor-specific molecular probes having a dye-quencher arrangement are employed. In preferred embodiments, a compact integrated optical source and detector device is used for fluorescence measurements. Continuous and real-time monitoring of the activity of one or multiple blood factors is provided. Such real-time information can be used to automatically control delivery of drugs such as coagulants and/or blood thinners.


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