The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2018
Filed:
Sep. 15, 2017
Case Western Reserve University, Cleveland, OH (US);
Anant Madabhushi, Shaker Heights, OH (US);
Mirabela Rusu, Cleveland, OH (US);
Case Western Reserve University, Cleveland, OH (US);
Abstract
Methods and apparatus distinguish invasive adenocarcinoma (IA) from in situ adenocarcinoma (AIS). One example apparatus includes a set of circuits, and a data store that stores three dimensional (3D) radiological images of tissue demonstrating IA or AIS. The set of circuits includes a classification circuit that generates an invasiveness classification for a diagnostic 3D radiological image, a training circuit that trains the classification circuit to identify a texture feature associated with IA, an image acquisition circuit that acquires a diagnostic 3D radiological image of a region of tissue demonstrating cancerous pathology and that provides the diagnostic 3D radiological image to the classification circuit, and a prediction circuit that generates an invasiveness score based on the diagnostic 3D radiological image and the invasiveness classification. The training circuit trains the classification circuit using a set of 3D histological reconstructions combined with the set of 3D radiological images.