The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

Jan. 26, 2015
Applicant:

Ohio State Innovation Foundation, Columbus, OH (US);

Inventors:

Ning Jin, Powell, OH (US);

Marie-Pierre Jolly, Hillsborough, NJ (US);

Orlando Simonetti, Columbus, OH (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01R 33/50 (2006.01); G01R 33/565 (2006.01); A61B 5/055 (2006.01); A61B 5/00 (2006.01); G01R 33/561 (2006.01);
U.S. Cl.
CPC ...
G01R 33/56509 (2013.01); A61B 5/055 (2013.01); A61B 5/7207 (2013.01); G01R 33/50 (2013.01); G01R 33/5616 (2013.01);
Abstract

A novel free-breathing myocardial T2* mapping combining multiple single-shot black-blood GRE-EPI images with automatic non-rigid motion correction. The present disclosure describes a method of accurate myocardial T2* measurements that is insensitive to respiratory motion, and is likely to reduce sensitivity to arrhythmia as well since each image is acquired in a single heart beat. The T2*-weighted GRE-EPI images are motion corrected using, e.g., automatic non-rigid motion correction to reduce mis-registration due to respiratory motion. A T2* map is calculated using the motion-corrected T2*-weighted images by fitting pixel intensities to a, e.g., two-parameter mono-exponential model.


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