The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

Dec. 06, 2013
Applicant:

Synthetic Genomics, Inc., La Jolla, CA (US);

Inventors:

Shaun Bailey, San Diego, CA (US);

Jay McCarren, Cardiff, CA (US);

Soyan Leung Lieberman, Solana Beach, CA (US);

Jonathan E. Meuser, San Diego, CA (US);

Anna E. Romano, Honolulu, HI (US);

Daniel Yee, San Diego, CA (US);

Leah Soriaga, San Diego, CA (US);

Robert C. Brown, San Diego, CA (US);

Ariel S. Schwartz, San Diego, CA (US);

Assignee:

Synthetic Genomics, Inc., La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C12N 1/12 (2006.01); C12N 15/01 (2006.01); C12N 1/36 (2006.01); C07K 14/405 (2006.01); C07K 14/415 (2006.01);
U.S. Cl.
CPC ...
C12N 15/825 (2013.01); C07K 14/405 (2013.01); C07K 14/415 (2013.01); C12N 1/12 (2013.01); C12N 1/36 (2013.01); C12N 15/01 (2013.01); C12N 15/8269 (2013.01);
Abstract

Mutant photosynthetic microorganisms having reduced chlorophyll and increased photosynthetic efficiency are provided. The mutants have a locked in high light-acclimated phenotype, in which many of the photosynthetic parameters characteristic of high light acclimated wild type cells are found in the LIHLA mutants when acclimated to low light, such as reduced chlorophyll, reduced NPQ, higher qP, higher E, higher Pper unit chlorophyll with little to no reduction in Pper cell, and higher rates of electron transport through photosystem II over a wide range of light intensities. Provided herein are constructs for attenuating or disrupting genes are provided for generating mutants having the LIHLA phenotype. Also provided are methods of culturing LIHLA mutants for the production of biomass or other products.


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