The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

May. 16, 2014
Applicants:

Saitama University, Saitama, Saitama, JP;

Nikon Corporation, Chiyoda-ku, Tokyo, JP;

Inventors:

Naoto Nemoto, Saitama, JP;

Yuuya Yotsumoto, Saitama, JP;

Assignees:

Saitama University, Saitama, JP;

Nikon Corporation, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); C12N 15/10 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1062 (2013.01); C07K 14/435 (2013.01); C07K 14/4702 (2013.01);
Abstract

The present invention improves in vitro virus synthesis efficiency and stability of mRNA derived from screened cDNA in a cDNA display method to improve the efficiency and reliability of the production of a peptide by a molecular evolutionary engineering technique. Provided is a ligand which comprises three fingers formed from antiparallel β-sheets and a loop region intercalated between the antiparallel β-sheets, wherein at least a fingertip part formed by the loop region of each of the fingers is bound to the target molecule, and wherein the ligand comprises the amino acid sequence of SEQ ID NO: 1. In the amino acid sequence of SEQ ID NO: 1, X7 represents an arbitrary amino acid residue that constitutes the fingertip part of each of the fingers, each numeric character represents the number of amino acid residues, and X7 and X4 are not composed of the same amino acid residues as each other.


Find Patent Forward Citations

Nemoto, Naoto. (2018). Ligand having three finger structure and a method for detecting a molecule by using thereof (U.S. Patent No. 9982254). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9982254

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