The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2018
Filed:
Mar. 10, 2014
Applicant:
Heidelberg Pharma Gmbh, Ladenburg, DE;
Inventors:
Christoph Müller, Birkenau, DE;
Jan Anderl, Modautal, DE;
Werner Simon, Hüffelsheim, DE;
Christian Lutz, Weinheim, DE;
Torsten Hechler, Bensheim, DE;
Assignee:
Heidelberg Pharma GmbH, Ladenburg, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/64 (2006.01); C07K 16/32 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C07K 7/64 (2013.01); A61K 47/6831 (2017.08); A61K 47/6851 (2017.08); A61K 47/6855 (2017.08); C07K 16/32 (2013.01);
Abstract
The invention relates to tumor therapy. In one aspect, the present invention relates to conjugates of an amatoxin and a target-binding moiety, e.g. an antibody, connected by certain linkages, which are useful in the treatment of cancer and other disorders and diseases. In a further aspect the invention relates to pharmaceutical compositions comprising such conjugates.