The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2018
Filed:
Oct. 14, 2016
Applicant:
Amgen, Inc., Thousand Oaks, CA (US);
Inventors:
David Bauer, Sudbury, MA (US);
Matthew Bio, Santa Barbara, CA (US);
Melanie Cooke, Arlington, MA (US);
Katrina W. Copeland, Sudbury, MA (US);
Matthew Peterson, Cambridge, MA (US);
Michele Potashman, Cambridge, MA (US);
Roman Shimanovich, Brighton, MA (US);
Helming Tan, Thousand Oaks, CA (US);
Assignee:
AMGEN INC., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61K 31/52 (2006.01); C07C 55/10 (2006.01); C07C 55/12 (2006.01); C07C 57/10 (2006.01); C07C 57/145 (2006.01); C07C 275/02 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 31/52 (2013.01); C07C 55/10 (2013.01); C07C 55/12 (2013.01); C07C 57/10 (2013.01); C07C 57/145 (2013.01); C07C 275/02 (2013.01); C07B 2200/13 (2013.01);
Abstract
Provided herein are novel polymorphic forms and co-crystals of a compound useful in the treatment, prevention, or amelioration of cancer. In particular, the invention provides polymorphs and co-crystals of 6-{(1R)-1-[8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one, which is an inhibitor of c-Met.