The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

May. 20, 2015
Applicants:

Abide Therapeutics, Inc., San Diego, CA (US);

The Scripps Research Institute, La Jolla, CA (US);

Inventors:

Benjamin F. Cravatt, La Jolla, CA (US);

Armand B. Cognetta, San Diego, CA (US);

Jonathan J. Hulce, San Diego, CA (US);

Micah J. Niphakis, San Diego, CA (US);

Todd K. Jones, Solana Beach, CA (US);

Cheryl A. Grice, Encinitas, CA (US);

Assignees:

ABIDE THERAPEUTICS, INC., San Diego, CA (US);

THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01); C12Q 1/34 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C12Q 1/34 (2013.01);
Abstract

Provided herein are N-hydroxy bicyclic hydantoin carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of serine hydrolases. Furthermore, the subject compounds and compositions are useful for the treatment of one or more of cancer, pain, diabetes, obesity/metabolic syndrome, epilepsy, traumatic brain injury, and inflammation.


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