The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

Jul. 20, 2015
Applicant:

Opko Diagnostics, Llc, Woburn, MA (US);

Inventors:

Vincent Linder, Tewksbury, MA (US);

David Steinmiller, Cambridge, MA (US);

Assignee:

OPKO Diagnostics, LLC, Woburn, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 35/08 (2006.01); B01L 3/00 (2006.01); G01N 21/59 (2006.01); G01N 33/543 (2006.01); G01N 33/574 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502746 (2013.01); B01L 3/5027 (2013.01); B01L 3/502715 (2013.01); G01N 21/59 (2013.01); G01N 33/54313 (2013.01); G01N 33/57434 (2013.01); B01L 7/52 (2013.01); B01L 2200/025 (2013.01); B01L 2200/026 (2013.01); B01L 2200/027 (2013.01); B01L 2200/028 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/143 (2013.01); B01L 2200/146 (2013.01); B01L 2200/147 (2013.01); B01L 2300/021 (2013.01); B01L 2300/027 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/1827 (2013.01); B01L 2300/1894 (2013.01); B01L 2400/0475 (2013.01); B01L 2400/0666 (2013.01); B01L 2400/082 (2013.01); G01N 2201/062 (2013.01); G01N 2201/0612 (2013.01); G01N 2201/0621 (2013.01); G01N 2201/0697 (2013.01); G01N 2333/96433 (2013.01); Y10T 137/0324 (2015.04); Y10T 436/12 (2015.01);
Abstract

Systems and methods for controlling fluids in microfluidic systems are generally described. In some embodiments, control of fluids involves the use of feedback from one or more processes or events taking place in the microfluidic system. For instance, a detector may detect one or more fluids at a measurement zone of a microfluidic system and one or more signals, or a pattern of signals, may be generated corresponding to the fluid(s). In some cases, the signal or pattern of signals may correspond to an intensity, a duration, a position in time relative to a second position in time or relative to another process, and/or an average time period between events. Using this data, a control system may determine whether to modulate subsequent fluid flow in the microfluidic system. In some embodiments, these and other methods can be used to conduct quality control to determine abnormalities in operation of the microfluidic system.


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