The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

Aug. 18, 2015
Applicant:

New York University, New York, NY (US);

Inventors:

Jasna Brujic, New York, NY (US);

Martin Haase, New York, NY (US);

Assignee:

NEW YORK UNIVERSITY, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 13/00 (2006.01); B01J 13/06 (2006.01); B01J 13/02 (2006.01); A61K 9/113 (2006.01); B01J 13/12 (2006.01); B01F 5/04 (2006.01); B01F 13/00 (2006.01); B01F 3/08 (2006.01); A61Q 19/00 (2006.01); A61K 8/11 (2006.01); A61K 8/14 (2006.01);
U.S. Cl.
CPC ...
B01J 13/00 (2013.01); A61K 8/11 (2013.01); A61K 8/14 (2013.01); A61K 9/113 (2013.01); A61Q 19/00 (2013.01); B01F 3/0807 (2013.01); B01F 5/045 (2013.01); B01F 13/0059 (2013.01); B01J 13/02 (2013.01); B01J 13/06 (2013.01); B01J 13/125 (2013.01); A61K 2800/10 (2013.01); A61K 2800/80 (2013.01);
Abstract

Multiple emulsions with an 'onion' topology are useful vehicles for drug delivery, biochemical assays, and templating materials. They can be assembled by ternary liquid phase separation using microfluidics, but the control over their design is limited because the mechanism of their creation is unknown. Here it is shown that phase separation occurs via self-similar cycles of mass transfer, spinodal decomposition or nucleation, and coalescence into multiple layers. Mapping out the phase diagram demonstrates a linear relation between concentric layer diameters, whose slope depends on the initial ternary composition and the molecular weight of the surfactant. These general rules quantitatively predict the number of droplet layers (multiplicity). Further, self-assembly routes for polymer capsules and liposomes are provided with techniques to assemble lipid-stabilized droplets with ordered internal structures.


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