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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9980976 B1

PDFFull Text
Date of Patent:
May. 29, 2018

Filed:

Feb. 17, 2016

Use of redd1 inhibitors to dissociate therapeutic and adverse atrophogenic effects of glucocorticoid receptor agonists

Applicant:

Northwestern University, Evanston, IL (US);

Inventors:

Irina Budunova, Chicago, IL (US);

Gleb Baida, Chicago, IL (US);

Joel Dudley, Rye, NY (US);

Assignee:

Northwestern University, Evanston, IL (US);

Attorney:

Andrus Intellectual Property Law, LLP

Primary Examiner:

My-Chau T Tran

Int. Cl.
CPC ...
A61K 31/56 (2006.01); A61K 31/436 (2006.01); A61K 45/06 (2006.01); A61K 31/407 (2006.01); A61K 31/4164 (2006.01); A61K 31/429 (2006.01); A61K 31/498 (2006.01); A61K 31/542 (2006.01); A61K 31/573 (2006.01); A61K 31/58 (2006.01); A61K 31/7076 (2006.01);
U.S. Cl.
CPC ...
A61K 31/56 (2013.01); A61K 31/407 (2013.01); A61K 31/4164 (2013.01); A61K 31/429 (2013.01); A61K 31/436 (2013.01); A61K 31/498 (2013.01); A61K 31/542 (2013.01); A61K 31/573 (2013.01); A61K 31/58 (2013.01); A61K 31/7076 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed are methods and pharmaceutical compositions for treating diseases, disorders, and conditions associated with glucocorticoid receptor (GR) expression and activity. The disclosed methods typically include administering to a patient in need thereof a glucocorticoid receptor (GR) agonist and administering to the patient in need thereof a REDD1 inhibitor that inhibits expression or activity of REDD1, wherein the REDD1 inhibitor is administered before, concurrently with, or after the GR agonist is administered.

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Budunova, Irina. (2018). Use of redd1 inhibitors to dissociate therapeutic and adverse atrophogenic effects of glucocorticoid receptor agonists (U.S. Patent No. 9980976). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9980976

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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