The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2018
Filed:
Feb. 17, 2016
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Assignee:
Northwestern University, Evanston, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/56 (2006.01); A61K 31/436 (2006.01); A61K 45/06 (2006.01); A61K 31/407 (2006.01); A61K 31/4164 (2006.01); A61K 31/429 (2006.01); A61K 31/498 (2006.01); A61K 31/542 (2006.01); A61K 31/573 (2006.01); A61K 31/58 (2006.01); A61K 31/7076 (2006.01);
U.S. Cl.
CPC ...
A61K 31/56 (2013.01); A61K 31/407 (2013.01); A61K 31/4164 (2013.01); A61K 31/429 (2013.01); A61K 31/436 (2013.01); A61K 31/498 (2013.01); A61K 31/542 (2013.01); A61K 31/573 (2013.01); A61K 31/58 (2013.01); A61K 31/7076 (2013.01); A61K 45/06 (2013.01);
Abstract
Disclosed are methods and pharmaceutical compositions for treating diseases, disorders, and conditions associated with glucocorticoid receptor (GR) expression and activity. The disclosed methods typically include administering to a patient in need thereof a glucocorticoid receptor (GR) agonist and administering to the patient in need thereof a REDD1 inhibitor that inhibits expression or activity of REDD1, wherein the REDD1 inhibitor is administered before, concurrently with, or after the GR agonist is administered.