The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

Mar. 09, 2015
Applicant:

Merck Patent Gmbh, Darmstadt, DE;

Inventors:

Bayard R. Huck, Sudbury, MA (US);

Erik Wilker, Lexington, MA (US);

Andreas Machl, Cambridge, MA (US);

Remigiusz Kaleta, Groton, MA (US);

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/517 (2013.01); A61K 39/395 (2013.01); A61K 39/39558 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01);
Abstract

The invention relates to combinations of 4-[(S)-2-Azetidin-1-yl-1-(4-chloro-3-trifluoromethyl-phenyl)-ethylamino]-quinazoline-8-carboxylic acid amide and/or its physiologically acceptable salts and solvates, and an inhibitor of Her2, and the use of such combinations for the treatment of cancer.


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