The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

Oct. 20, 2015
Applicant:

Toray Industries, Inc., Tokyo, JP;

Inventors:

Yoichiro Koshi, Kamakura, JP;

Reiji Nishio, Kamakura, JP;

Yoshinori Kakizawa, Kamakura, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 39/39 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1682 (2013.01); A61K 9/1623 (2013.01); A61K 9/1641 (2013.01); A61K 9/1647 (2013.01); A61K 9/1652 (2013.01); A61K 39/0011 (2013.01); A61K 39/39 (2013.01); A61K 2039/55583 (2013.01); A61K 2039/6087 (2013.01); A61K 2039/6093 (2013.01);
Abstract

A process of producing an immunogenic particle includes mixing an aqueous solvent A wherein an antigen(s) is/are dissolved and a water-immiscible organic solvent B wherein an amphiphilic polymer(s) whose hydrophobic segment(s) is/are poly(hydroxy acid) is/are dissolved, to form a reversed-phase emulsion; and removing the solvent from the reversed-phase emulsion to obtain an antigen-adjuvant microparticle complex, wherein the aqueous solvent A and/or the water-immiscible organic solvent B contains a surfactant.


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