The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

Jan. 16, 2015
Applicant:

Konica Minolta, Inc., Chiyoda-ku, Tokyo, JP;

Inventor:

Takeshi Isoda, Sayama, JP;

Assignee:

KONICA MINOLTA, INC., Chiyoda-Ku, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 8/14 (2006.01); A61K 8/41 (2006.01); A61K 8/49 (2006.01); A61K 8/63 (2006.01); A61K 8/68 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); A61K 49/04 (2006.01); A61Q 11/00 (2006.01); A61Q 19/00 (2006.01); B01J 13/02 (2006.01); C12N 15/88 (2006.01); A61K 31/7088 (2006.01); A61K 49/00 (2006.01); A23P 10/30 (2016.01); A61K 47/62 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 9/1277 (2013.01); A23P 10/30 (2016.08); A61K 8/14 (2013.01); A61K 8/416 (2013.01); A61K 8/4986 (2013.01); A61K 8/63 (2013.01); A61K 8/68 (2013.01); A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 47/62 (2017.08); A61K 47/6911 (2017.08); A61K 49/0002 (2013.01); A61K 49/0466 (2013.01); A61Q 11/00 (2013.01); A61Q 19/00 (2013.01); B01J 13/02 (2013.01); C12N 15/88 (2013.01); C12N 2810/85 (2013.01);
Abstract

It is intended to provide a liposome preparation which is a liposome, has a lipid bilayer membrane composed of an inner membrane constituted by a lipid including one or more types of functional lipids (a lipid capable of chemically interacting with another compound such as a charged lipid, a polarizable lipid, a lipid-soluble lipid or a water-soluble lipid) and an outer membrane constituted by a lipid with or without including one or more types of functional lipids, and is characterized in that at least a condition that the amount of any one type of functional lipid contained in the inner membrane is larger than in the outer membrane is satisfied. The liposome preparation is suitable as a liposome for encapsulating a contrast agent (a neutral substance having a hydroxy group), siRNA (an anionic substance) having an anticancer activity or the like. Its encapsulation ratio of drug agents, dispersion stability, control release and the like have been improved.


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