The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2018

Filed:

Dec. 19, 2014
Applicant:

L'oreal, Paris, FR;

Inventors:

Aziz Fadli, Chelles, FR;

Stéphane Blais, Palaiseau, FR;

Assignee:

L'OREAL, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61Q 5/10 (2006.01); A61K 8/49 (2006.01); C07D 471/04 (2006.01); A61Q 5/06 (2006.01);
U.S. Cl.
CPC ...
A61K 8/494 (2013.01); A61Q 5/065 (2013.01); A61Q 5/10 (2013.01); C07D 471/04 (2013.01); A61K 2800/4324 (2013.01);
Abstract

The invention relates to a 1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-amine compound of formula (I) below, addition salts thereof, optical isomers, geometrical isomers and tautomers thereof and/or solvates thereof: in which: .R, R, R, R, and Rindependently represent: a hydrogen or halogen atom; a C-Calkyl radical; a C-Chydroxyalkyl radical; a carboxyl radical; a (C-C)alkoxycarbonyl radical; .R1 and R6, which may be identical or different, represent: hydrogen atom; C-Cand preferably Ci-C6 alkyl radical,—optionally interrupted with one or more heteroatoms chosen from O and S or with one or more groups—NR and/or—optionally terminating with at least one group—NXXor at least one group —OX, .Xand X2 independently denote—a hydrogen atom, a linear C-Calkyl radical, a branched C-Calkyl radical, a linear C-Chydroxyalkyl radical or a branched C-Chydroxyalkyl radical, X1 and X2 may form, with the nitrogen atom that bears them, a saturated or unsaturated 5- to 8-membered heterocycle, in which one of the ring members may be a heteroatom chosen from O, S and N; the said heterocycle possibly being substituted with one or more linear or branched C-Calkyl or C-Chydroxyalkyl radicals, .X3 denotes—a hydrogen atom—a linear C1-C4 or branched C3-C4 alkyl radical, and .R denotes—a hydrogen atom—a linear C1-C4 alkyl radical.


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