The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2018
Filed:
Jun. 17, 2011
David D. Nolte, Lafayette, IN (US);
Kwan Jeong, Seoul, KR;
David D. Nolte, Lafayette, IN (US);
Kwan Jeong, Seoul, KR;
PURDUE RESERACH FOUNDATION, West Lafayette, IN (US);
Abstract
Motility contrast imaging (MCI) is a depth-resolved holographic technique to extract cellular and subcellular motion inside tissue. The holographic basis of the measurement technique makes it highly susceptible to mechanical motion. The motility contrast application, in particular, preferably includes increased mechanical stability because the signal is based on time-varying changes caused by cellular motion, not to be confused with mechanical motion of the system. The use of the resulting spectrogram response signatures, or 'fingerprint' data, of known compounds is disclosed to screen new compounds for leads as to those having potentially beneficial mechanisms of action. The 'fingerprint' data of known toxic compounds can be used to screen new compounds for toxicity.