The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2018

Filed:

Jul. 26, 2016
Applicants:

Agency for Science, Technology and Research, Singapore, SG;

Singapore Health Services Pte Ltd., Singapore, SG;

Inventors:

Sai Kiang Lim, Singapore, SG;

Kok Hian Tan, Singapore, SG;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/00 (2006.01); G01N 33/68 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/689 (2013.01); G01N 33/5091 (2013.01); G01N 33/6872 (2013.01); G01N 33/6893 (2013.01); G01N 2333/47 (2013.01); G01N 2405/10 (2013.01); G01N 2800/32 (2013.01); G01N 2800/368 (2013.01); G01N 2800/52 (2013.01); G01N 2800/7028 (2013.01);
Abstract

We describe a method of monitoring the state of a cell, tissue, organ or organism. The method comprises establishing, for a sample of micro-particles from the cell, tissue, organ or organism, a ratio. The ratio is of a selected polypeptide in microparticles which comprise GM1 gangliosides, preferably which bind to Cholera Toxin B (CTB) ('GM1 ganglioside microparticle polypeptide') to the selected polypeptide in microparticles which comprise exposed phosphotidylserine, preferably which bind to Annexin V ('Annexin V microparticle polypeptide'). The GM1 ganglioside microparticle polypeptide to Annexin V microparticle polypeptide ratio so established may be indicative of the state of the cell, tissue, organ or organism.


Find Patent Forward Citations

Lim, Sai. (2018). Microparticle fractionation (U.S. Patent No. 9977032). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9977032

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…