The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2018

Filed:

Apr. 01, 2015
Applicant:

Nitto Denko Corporation, Osaka, JP;

Inventors:

Kenjiro Minomi, Osaka, JP;

Hirokazu Takahashi, Osaka, JP;

Erika Terada, Osaka, JP;

Yoshiro Niitsu, Hokkaido, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12N 15/113 (2010.01); A61K 9/127 (2006.01); A61K 31/713 (2006.01); A61K 38/17 (2006.01); A61K 47/64 (2017.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/1271 (2013.01); A61K 31/713 (2013.01); A61K 38/00 (2013.01); A61K 38/1703 (2013.01); A61K 47/64 (2017.08); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01);
Abstract

Provided are: a targeting molecule targeting a target cell which is selected from the group consisting of a stellate cell, a myofibroblast, a cancer-associated fibroblast, a tumor cell and a cell expressing STRA6, said targeting molecule being selected from the group consisting of (1) a peptide containing an amino acid sequence in the cell-binding region of RBP, (2) a variant peptide of the aforesaid peptide (1), said variant peptide having a comparable targetability to peptide (1), and (3) a peptide mimetic having a comparable targetability to peptide (1) or peptide (2); a targeting agent, a carrier, a complex and a medicinal composition each comprising the targeting molecule; a method for treating, examining, diagnosing or monitoring a disease related to the aforesaid target cell; a method for labeling, detecting or imaging the target cell, etc.


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