The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2018
Filed:
Jun. 13, 2014
Applicant:
Joslin Diabetes Center, Inc., Boston, MA (US);
Inventors:
Yu-Hua Tseng, Newton, MA (US);
Hongbin Zhang, Allston, MA (US);
Assignee:
Joslin Diabetes Center, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C12N 15/113 (2010.01); A61K 31/517 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/517 (2013.01); C12N 5/0653 (2013.01); C12N 2310/141 (2013.01); C12N 2320/30 (2013.01);
Abstract
This invention reveals a novel miRNA and a novel miRNA-regulated signaling network which controls brown adipogenesis and thermogenic programs, thereby providing a powerful approach for the treatment of obesity and related metabolic diseases. In this regard, the present invention is also directed towards methods of treatment of obesity and excess weight (overweight) and metabolic disorders caused by or aggravated by a subject being overweight or obese.