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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9976130 B1

PDFFull Text
Expired
Date of Patent:
May. 22, 2018

Filed:

Dec. 30, 2016

Opaa fl—a mutant enzyme with increased catalytic efficiency on organophosphorus compound gd

Applicant:

U.s. Army Edgewood Chemical Biological Center, Washington, DC (US);

Inventors:

Mark A Guelta, White Marsh, MD (US);

Melissa M. Dixon, Abingdon, MD (US);

Steven P. Harvey, Lutherville, MD (US);

Assignee:

The United States of America as Represented by the Secretary of the Army, Washington, DC (US);

Attorney:

Ulysses John Biffoni

Primary Examiner:

Richard C Ekstrom

Int. Cl.
CPC ...
C12N 9/16 (2006.01); A61K 38/46 (2006.01); A62D 3/02 (2007.01); A62D 101/02 (2007.01); A62D 101/04 (2007.01); A62D 101/26 (2007.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/16 (2013.01); A61K 38/465 (2013.01); A62D 3/02 (2013.01); C12Y 301/08002 (2013.01); A61K 38/00 (2013.01); A62D 2101/02 (2013.01); A62D 2101/04 (2013.01); A62D 2101/26 (2013.01);
Abstract

This invention is directed toward a non-wild-type organophosphorus acid anhydrolase enzyme having two site mutations, method of production, and method of use to more effectively degrade toxic organophosphorus compounds and, in particular, toxic chemical GD (3,3-Dimethylbutan-2-ylmethylphosphonofluoridate), than the wild type organophosphorus acid anhydrolase.

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Guelta, Mark. (2018). Opaa fl—a mutant enzyme with increased catalytic efficiency on organophosphorus compound gd (U.S. Patent No. 9976130). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9976130

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