The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2018
Filed:
Dec. 30, 2016
Applicant:
U.s. Army Edgewood Chemical Biological Center, Washington, DC (US);
Inventors:
Mark A Guelta, White Marsh, MD (US);
Melissa M. Dixon, Abingdon, MD (US);
Steven P. Harvey, Lutherville, MD (US);
Assignee:
The United States of America as Represented by the Secretary of the Army, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); A61K 38/46 (2006.01); A62D 3/02 (2007.01); A62D 101/02 (2007.01); A62D 101/04 (2007.01); A62D 101/26 (2007.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/16 (2013.01); A61K 38/465 (2013.01); A62D 3/02 (2013.01); C12Y 301/08002 (2013.01); A61K 38/00 (2013.01); A62D 2101/02 (2013.01); A62D 2101/04 (2013.01); A62D 2101/26 (2013.01);
Abstract
This invention is directed toward a non-wild-type organophosphorus acid anhydrolase enzyme having two site mutations, method of production, and method of use to more effectively degrade toxic organophosphorus compounds and, in particular, toxic chemical GD (3,3-Dimethylbutan-2-ylmethylphosphonofluoridate), than the wild type organophosphorus acid anhydrolase.