The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2018
Filed:
Jul. 21, 2016
Applicant:
Baylor College of Medicine, Houston, TX (US);
Inventors:
David Spencer, Houston, TX (US);
Priyadharshini Narayanan, Houston, TX (US);
Assignee:
BAYLOR COLLEGE OF MEDICINE, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12N 15/86 (2006.01); C12N 5/0784 (2010.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C12N 9/90 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0639 (2013.01); C07K 14/4702 (2013.01); C07K 14/4705 (2013.01); C07K 14/70578 (2013.01); C12N 7/00 (2013.01); C12N 9/90 (2013.01); C12N 15/86 (2013.01); C12Y 502/01008 (2013.01); A61K 39/00 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5156 (2013.01); C07K 2319/033 (2013.01); C12N 2501/52 (2013.01); C12N 2501/70 (2013.01); C12N 2501/998 (2013.01); C12N 2510/00 (2013.01); C12N 2710/10343 (2013.01);
Abstract
Provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing an inducible pattern recognition receptor adapter, or adapter fragment, and CD40 activity. Also provided are nucleic acid compositions comprising sequences coding for chimeric proteins that include an inducible CD40 peptide and an inducible pattern recognition receptor adapter or adapter fragment.