The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2018

Filed:

Jan. 19, 2017
Applicants:

Biogen International Neuroscience Gmbh, Zug, CH;

University of Zürich, Zürich, CH;

Inventors:

Andreas Weihofen, Belmont, MA (US);

Jan Grimm, Dubendorf, CH;

Christoph Hock, Erlenbach, CH;

Roger Nitsch, Zumikon, CH;

Lihe Su, Reading, MA (US);

Paul Weinreb, Andover, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C12P 21/08 (2006.01); C07K 16/18 (2006.01); G01N 33/68 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 47/48538 (2013.01); G01N 33/6896 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); G01N 2333/47 (2013.01); G01N 2800/28 (2013.01); G01N 2800/2828 (2013.01); G01N 2800/2835 (2013.01);
Abstract

Provided are anti-human α-synuclein-specific binding molecules, e.g., antibodies or antiben-binding fragments, variants or derivatives thereof, as methods related thereto. Further provided are anti-human α-synuclein binding molecules which bind to specific N-terminal and C-terminal epitopes on human α-synuclein. The binding molecules described herein can be used in pharmaceutical and diagnostic compositions for α-synuclein targeted immunotherapy and diagnosis, respectively.


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