The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2018

Filed:

Mar. 14, 2014
Applicant:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Ralph Steven Baric, Haw River, NC (US);

Lisa Chon Lindesmith, Apex, NC (US);

Kari Moore Debbink, Durham, NC (US);

Eric Francis Donaldson, Durham, NC (US);

Jesica Anne Swanstrom, Morrisville, NC (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/00 (2006.01); C07K 14/005 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); G01N 33/56983 (2013.01); C12N 2770/16022 (2013.01); C12N 2770/16034 (2013.01); C12N 2770/36143 (2013.01); G01N 2333/08 (2013.01);
Abstract

The present invention provides methods and compositions comprising a chimeric norovirus capsid protein comprising a norovirus VP1 major capsid protein backbone comprising a norovirus epitope selected from the group consisting of: a) Epitope A; b) Epitope B; c) Epitope C; d) Epitope D; e) Epitope E; f) Epitope F; and g) any combination of (a) through (f) above, wherein the norovirus epitope is from a norovirus strain that is different from the norovirus VP1 major capsid protein backbone.


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