The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2018
Filed:
Aug. 02, 2016
Glenmark Pharmaceuticals S.a., La Chaux-de-Fonds, CH;
Sanjib Das, West Bengal, IN;
Laxmikant A. Gharat, Maharashtra, IN;
Rajendra L. Harde, Maharashtra, IN;
Sandeep Y. Shelke, Maharashtra, IN;
Shailesh R. Pardeshi, Maharashtra, IN;
Abraham Thomas, Maharashtra, IN;
Neelima Khairatkar-Joshi, Maharashtra, IN;
Daisy M. Shah, Maharashtra, IN;
Malini Bajpai, Uttra Pradesh, IN;
GLENMARK PHARMACEUTICALS S.A., La Chaux-de-Fonds, CH;
Abstract
The present disclosure is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein ring A, ring B, L, R, R, R, R, R, R, R, n, m, p and q are as defined herein, which are active as modulators of retinoid-related orphan receptor gamma t (RORγt). These compounds prevent, inhibit, or suppress the action of RORγt and are therefore useful in the treatment of RORγt mediated diseases, disorders, syndromes or conditions such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative diseases and cancer.