The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2018
Filed:
Jun. 03, 2014
Applicant:
Julius-maximilians-universitaet Wuerzburg, Wuerzburg, DE;
Inventors:
Manik Chatterjee, Wuerzburg, DE;
Andreas Hartung, Rannungen, DE;
Ulrike Holzgrabe, Eibelstadt, DE;
Elisabeth Mueller, Wuerzburg, DE;
Ulrich Peinz, Peine, DE;
Christoph Sotriffer, Gerbrunn, DE;
David Zilian, Wuerzburg, DE;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/16 (2006.01); C07D 217/26 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 217/26 (2013.01); C07D 401/12 (2013.01);
Abstract
The present invention relates to tetrahydroisoquinolinone derivatives, a pharmaceutical composition comprising the same and the use of these derivatives in the inhibition of the Hsp70 protein. The compounds are useful in the treatment or inhibition of cancer, autoimmune disease, rheumatoid arthritis, inflammatory bowel disease and psoriasis.