The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2018
Filed:
Jan. 13, 2017
Fujifilm Corporation, Tokyo, JP;
Naoyuki Nishikawa, Ashigarakami-gun, JP;
Makoto Ono, Ashigarakami-gun, JP;
Susumu Sugiyama, Ashigarakami-gun, JP;
Yoshihide Iwaki, Ashigarakami-gun, JP;
FUJIFILM Corporation, Tokyo, JP;
Abstract
An object of the present invention is to provide lipid particles which have low cytotoxicity, can stably hold nucleic acid molecules outside cells, and can promptly release nucleic acids in cytoplasm after escaping from endosome, and a nucleic acid delivery carrier. According to the present invention, there are provided lipid particles containing a compound represented by the following General Formula (1), sterol, at least one lipid selected from the group consisting of a neutral lipid and a lipid having a polyethylene glycol chain, and nucleic acids, and a nucleic acid delivery carrier. In the formula, Rand Rare the same as or different from each other, and are alkyl groups having 10 to 22 carbon atoms.