The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2018

Filed:

Apr. 04, 2017
Applicant:

Galectin Therapeutics, Inc., Norcross, GA (US);

Inventors:

Eliezer Zomer, Newton, MA (US);

Peter G. Traber, Duluth, GA (US);

Anatole A. Klyosov, Newton, MA (US);

Elena Chekhova, Cambridge, MA (US);

Assignee:

Galectin Therapeutics, Inc., Norcross, GA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C08B 37/00 (2006.01); C08B 37/06 (2006.01); A61K 31/715 (2006.01); A61K 31/732 (2006.01); A61K 45/06 (2006.01); A61K 31/738 (2006.01);
U.S. Cl.
CPC ...
A61K 31/715 (2013.01); A61K 31/738 (2013.01); A61K 45/06 (2013.01); C08B 37/006 (2013.01); C08B 37/0045 (2013.01);
Abstract

Aspects of the invention provide compositions for use in the treatment galectin-dependent diseases. In particular, compositions comprising a selectively depolymerized, branched galactoarabino-rhamnogalacturonate whose backbone is predominantly comprised of 1,4-linked galacturonic acid (GalA) moieties, with a lesser backbone composition of alternating 1,4-linked GalA and 1,2-linked rhamnose (Rha), which in-turn is linked to any number of side chains, including predominantly 1,4-b-D-galactose (Gal) and 1,5-α-L-arabinose (Ara) residues.


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