The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Feb. 03, 2014
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Jochen Schmitz, San Francisco, CA (US);
Martin Oft, Palo Alto, CA (US);
Robert A. Kastelein, Portola Valley, CA (US);
J. Fernando Bazan, Menlo Park, CA (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/00 (2006.01); G01N 33/68 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); A61K 38/20 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6869 (2013.01); A61K 38/20 (2013.01); C07K 16/244 (2013.01); C07K 16/2866 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01);
Abstract
Provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders, including tumors and cancer. Also provided are methods of administering agonists or antagonists of IL-33 and IL-33 receptor.