The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2018

Filed:

Sep. 26, 2011
Applicant:

Todd M. Kinsella, Redwood City, CA (US);

Inventor:

Todd M. Kinsella, Redwood City, CA (US);

Assignee:

RIGEL PHARMACEUTICALS, INC., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/00 (2006.01); C07H 21/04 (2006.01); G01N 33/50 (2006.01); C12Q 1/68 (2018.01); C12N 15/10 (2006.01); C12N 15/79 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5061 (2013.01); C12N 15/1055 (2013.01); C12Q 1/6897 (2013.01); C07H 21/04 (2013.01); C07K 2319/92 (2013.01); C12N 15/79 (2013.01); C12N 2510/00 (2013.01); C12N 2800/00 (2013.01); C12N 2800/10 (2013.01);
Abstract

A construct system for expressing a reporter protein, as well as a transgenic animal and a screening method employing the same, are provided. In certain embodiments, the construct system is a three component system in which expression of a reporter protein from a reporter construct is induced by a transcription factor that is produced using two other constructs, each producing a different part of the transcription factor. The parts of the transcription factor are ligated together. Expression of the reporter only occurs in tissues in which both of the parts of the transcription factor are produced.


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