The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2018

Filed:

Apr. 14, 2015
Applicants:

Susan Buckhout-white, Silver Spring, MD (US);

Mario Ancona, Alexandria, VA (US);

Ellen R. Goldman, Germantown, MD (US);

Igor L. Medintz, Springfield, VA (US);

Joseph S. Melinger, Oakton, VA (US);

Inventors:

Susan Buckhout-White, Silver Spring, MD (US);

Mario Ancona, Alexandria, VA (US);

Ellen R. Goldman, Germantown, MD (US);

Igor L. Medintz, Springfield, VA (US);

Joseph S. Melinger, Oakton, VA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6818 (2013.01); G01N 21/6428 (2013.01);
Abstract

The invention relates to a nanoscale antenna including a nucleic acid scaffold having a structure selected from the group consisting of a Holliday junction, a star, and a dendrimer; and a plurality of fluorophores attached to the scaffold and configured as a FRET cascade comprising at least three different types of fluorophores, arranged with (a) a plurality of initial donor fluorophores fixed in exterior positions on the structure, (b) a terminal acceptor fluorophore fixed in a central position on the structure, and (c) a plurality of intermediate fluorophores fixed in positions on the scaffold between the initial acceptor fluorophores and the terminal acceptor fluorophores.


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