The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Nov. 23, 2015
Applicant:
Case Western Reserve University, Cleveland, OH (US);
Inventors:
Paul J. Tesar, Wickliffe, OH (US);
Robert H. Miller, Cleveland Heights, OH (US);
Fadi J. Najm, University Heights, OH (US);
Assignee:
Case Western Reserve University, Cleveland, OH (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/30 (2015.01); C12N 5/079 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0622 (2013.01); A61K 35/30 (2013.01); C12N 2501/01 (2013.01); C12N 2501/105 (2013.01); C12N 2501/115 (2013.01); C12N 2501/13 (2013.01); C12N 2501/135 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/385 (2013.01); C12N 2501/41 (2013.01); C12N 2501/727 (2013.01); C12N 2506/02 (2013.01);
Abstract
The present invention provides methods for generating oligodendrocyte progenitor cells from pluripotent cells, as well as methods for sustaining these oligodendrocyte progenitor cells in relatively pure cultures for long periods of time. The present invention also provides methods for further differentiating these oligodendrocyte progenitor cells into various glial cells.